Marijuana used for recreational and medical use comes from seeds, buds, roots, stems, and leaves of the marijuana plant. It has around 60 cannabinoids with its main compound ingredient being -9-tetrahydrocannabinol or THC.
Other People say marijuana smokers may encounter some side effects on the nervous system. This is when the psychoactive compounds found in marijuana THC in particular, enters the body and gets into the bloodstream; it gets into the brain and eventually coming across the natural cannabinoid receptors of the body. The THC then connects itself to these receptors in the nerve cells.
Marijuana users whose brain has not fully developed risk suffering from memory problems. When they age, neurons in the hippocampus are lost naturally leading to the memory problems, loss of sleep, impaired coordination and learning issues.
The hippocampus is one of the parts of the brain with high concentrations of cannabinoid receptors. This region manages short term memory hence marijuana use can hinder recollection of recent events. Other regions affected include the cerebellum and basal ganglia, responsible for control coordination and involuntary muscle movements respectively. When someone abuses marijuana, impaired motor skills, mood alterations, distorted time and sensory perception, decreased memory, and trouble thinking clearly and solving problems are all common short-term side effects.
Cannabis has over 480 natural components. Once injected to the body, terpenes natural chemicals give patients relief from their pain. The special receptors are part of the endocannabinoid system (ECS), which helps to modulate the functions of the body, including sleep, appetite, anxiety levels, and cognition. The ECS is connected to the immune and the nervous system.
Various studies that have been carried out on cannabis show that it has neiroprotective effects hence it support the health of spinal cord and the brain. It also helps in treating of various Central Nervous System disorders. Cannabis has cannabinoids that comprises of cannabidiol (CBD) and tetrahydrocannabinol (THC). The two substances have shown that they can effectively offer protection to neurons and astrocytes damage, modulate inflammatory reaction and assist in neuroregeneration.
The cannabinoid receptors (CB1 and CB2) of the endocannabinoid system, are activated by CBD and THC which plays a significant regulatory role in health. The upregulation of the endocannabinoid system has shown to lessen the extremity of symptoms like muscle spasms andneuropathic pain thus slowing down the progression of central nervous system disorders like multiple sclerosis, Parkinson’s disease, epilepsy, , Alzheimer’s disease among others. Studies also indicate that seizures caused by epilepsy, spasms experienced by those with multiple sclerosis and the neurological damage caused by spinal cord and traumatic brain injuries can be reduced by cannabinoids.
A condition referred to as endocannabinoid deficiency is caused by shortage of endocannabinoids which causes diseases that have to do with the immune and nervous system. Conditions include pain, inflammation, and nausea. These molecules are important for balance and good health.
There is a strong attraction of the THC that binds with cells in the glands, gonads, brain, connective tissue, and the central nervous system’s CB1 receptors. This is why when consuming cannabis with a higher amount of THC has such a potent effect. It can relieve pain symptoms, nausea or depression, giving lifestyle users a strong sense of euphoria. THC is effective for those going through chemotherapy, as well as conditions that cause inflammation, such as lupus and arthritis.
If CBI is more than average in a patient then they will be extremely sensitive to THC. However, if a patient has less than the average number of receptors, such as CB2 it will cause the person to experience little therapeutic effects to CBD. In this case, the person may need to consume greater amounts or add THC and terpenes that target other receptors.
University of California, San Diego (UCSD) School of Medicine, conducted a research on long-term marijuana users but their analysis failed to reveal considerable systematic effect on the neurocognitive functioning of users. The study which sampled 704 long-term marijuana users and 484 non users revealed very little evidence of deleterious effects and small effect of learning new information, said the study's senior author, Igor Grant.
